Hold Hands is a gimmicky move. It has no battle-use other than spending a turn.
The thing with Frustration, it is usable.. just hard to set up because if you've touched your poke.. you'd have to trade it to a friend, then get it back to get to base happiness.. then while in your party, stand right in front of the pc, feed it bitter medicines, and put it back in your PC permanently with the move..